Reactivation-Dependent Amnesia for Contextual Fear Memories: Evidence for Publication Bias
نویسندگان
چکیده
منابع مشابه
Reactivation-dependent amnesia for appetitive memories is determined by the contingency of stimulus presentation.
Previously acquired aversive and appetitive memories are not stable and permanent. The reactivation of such memories by re-exposure to training stimuli renders them vulnerable to disruption by amnestic agents such as the noncompetitive N-methyl-D-aspartate receptor antagonist (+)-5-methyl-10,11-dihydro-SH-dibenzo{a,d}cyclohepten-5,10-imine maleate (MK-801). However, relatively little is known a...
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Cumulative evidence indicates that the hippocampus plays a time-limited role in contextual learning paradigms. Pharmacological studies have indicated that acquisition of background contextual cues during Pavlovian fear conditioning is dependent upon hippocampal function, whereas early inactivation of the hippocampus after training produces retrograde amnesia. When administered prior to contextu...
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Evidence suggests that extinction, the suppression of a learned response to a Pavlovian signal that is produced by exposure to the signal alone after conditioning, is a consequence of new inhibitory learning. However, it has been proposed that extinction given immediately after conditioning reflects memory 'erasure'. Using contextual fear conditioning, we examine the nature of extinction furthe...
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سخن سردبیر editorial مجله دانشگاه علوم پزشکی رفسنجان دوره 14، مهر 1394، 534-533 راه حل های ارائه شده برای تورش انتشار the solutions offered for publication bias محسن رضائیان[1] m. rezaeian در سخن سردبیری شماره پیشین مجله دانشگاه به پدیده تورش انتشار پرداختیم و آن را به معنای انتشار بیشتر مقالاتی با نتیجه مثبت و یا نتیجه معنی دار آماری تعریف کردیم. همچنین، مختصری از تاریخچه بررسی تور...
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The basolateral amygdala (BLA) and the dorsal hippocampus (dHPC) are both structures with key roles in contextual fear conditioning. During fear conditioning, it is postulated that contextual representations of the environment are formed in the hippocampus, which are then associated with foot shock in the amygdala. However, it is not known to what extent a functional connection between these tw...
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ژورنال
عنوان ژورنال: eneuro
سال: 2020
ISSN: 2373-2822
DOI: 10.1523/eneuro.0108-20.2020